I recently registered a domain with the keywords: speed and site in it.
My web host had some problems with the server for whatever reason so a search on my keywords does not show my site at all last time I checked.
But I expect to hit #1 soon since I have been building great content compared to my lame competition.
The key is to outdo your competitors with way better content than they can ever hope to achieve.
If you have passion and drive, then it is easy!