It is easy to make wordpress appear as a regular website (even to the search engines) with all the different seo and content plugins available so I voted no to your question.
I have a few mini sites and a number of autoblogs that do ok for how young they are.
I do write about a years worth of material (15-30 articles so there is atleast 2 new articles a month) per site though and have it post them on a schedule so they are more or less set and forget sites unless something changes in one of the niches during the year and then I will probably insert some more that is relevant to whatever the change may be.
As for mini sites it depends how "mini" you mean, like if it is only 1 or 2 pages I would more than likely just create those using dreamweaver or another web design program but if you are talking about a site with more than that I would certainly go with wordpress.
Anyway, that is my opinion on this question